Analysis of the interactions between asbestos fibers and DNA has shown that phagocytosed fibers are able to make contact with chromosomes, often adhering to the chromatin fibers or becoming entangled within the chromosome. This contact between the asbestos fiber and the chromosomes or structural proteins of the spindle apparatus can induce complex abnormalities. The most common abnormality is monosomy of chromosome 22. Other frequent abnormalities include structural rearrangement of 1p, 3p, 9p and 6q chromosome arms.
Asbestos is imported into the United States and was even mined in the country during the 20th century. In the US, the use of asbestos peaked in 1973 when it amounted to 803,000 metric tons before declining to 1,700 metric tons in 2007. Industrial workers employed in settings such as manufacturing, construction and shipbuilding prior to 1980s are the ones who are at most risk, as federal safety regulation was not in place at the that time. Exposure continues to occur today because of the demolition of buildings in which asbestos was used during construction.
Cathy and I would like to extend our most sincere thanks to Jim Early, Bob Sweeney and your entire staff for the caring and professionalism in which you handled our Mesothelioma case. We are more than pleased with the settlements you have secured on our behalf and honestly, never expected such results.
Did you know?The asbestos industry was aware of the dangers of asbestos as early as the 1930’s. Yet, companies continued making and selling asbestos products. These products were used in homes, schools and throughout the military. These companies are legally responsible for exposing mesothelioma sufferers to asbestos.
Surgery, by itself, has proved disappointing. In one large series, the median survival with surgery (including extrapleural pneumonectomy) was only 11.7 months. However, research indicates varied success when used in combination with radiation and chemotherapy (Duke, 2008), or with one of the latter. A pleurectomy/decortication is the most common surgery, in which the lining of the chest is removed. Less common is an extrapleural pneumonectomy (EPP), in which the lung, lining of the inside of the chest, the hemi-diaphragm and the pericardium are removed. In localized pericardial mesothelioma, pericardectomy can be curative; when the tumor has metastasized, pericardectomy is a palliative care option. The entire tumor is not often able to be removed.
Most well-regarded mesothelioma law firms will offer free consultations for interested clients. This opportunity allows you to clear up any preliminary questions, get comfortable with the people who will potentially be handling your case, and familiarize yourself with the process ahead of you. During this initial consultation, you will likely want to bring forward questions to evaluate the law firm and see whether they are the right firm for you. Here are a few inquiries you may want to consider bringing to the table.
Prevention centers around reducing exposure to asbestos. Treatment often includes surgery, radiation therapy, and chemotherapy. A procedure known as pleurodesis, which involves using substances such as talc to scar together the pleura, may be used to prevent more fluid from building up around the lungs. Chemotherapy often includes the medications cisplatin and pemetrexed. The percentage of people that survive five years following diagnosis is on average 8% in the United States.
Commercial asbestos mining at Wittenoom, Western Australia, took place from 1937 to 1966. The first case of mesothelioma in the town occurred in 1960. The second case was in 1969, and new cases began to appear more frequently thereafter. The lag time between initial exposure to asbestos and the development of mesothelioma varied from 12 years 9 months up to 58 years. A cohort study of miners employed at the mine reported that 85 deaths attributable to mesothelioma had occurred by 1985. By 1994, 539 reported deaths due to mesothelioma had been reported in Western Australia.